Brigham and Women's Hospital, Boston



Findings on Opioids Detailed by Researchers at Brigham and Women's Hospital (Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care)

By a News Reporter-Staff News Editor at Drug Week Fresh data on Opioids are presented in a new report. According to news reporting from Boston, Massachusetts, by NewsRx journalists, research stated, "There is increasing concern among primary care practitioners about the use of opioids for chronic pain, including their adverse effects, but little attention has been given to how reports of side effects from prescription medication can contribute to outcomes among patients with chronic pain. The aim of this study was to investigate the impact of frequently reported side effects on mood, disability, and opioid misuse in patients with chronic pain prescribed opioids within primary care."

The news correspondents obtained a quote from the research from Brigham and Women's Hospital, "Two hundred (N=200) patients with chronic pain taking opioids for pain were recruited into the study. All patients completed baseline measures and a monthly side effects checklist once a month for 6 months. Patients were divided evenly based on a median split of the number of endorsed side effects over 6 months. The subjects repeated the baseline measures at the end of the study period. Over time, reports of medication side effects tended to decrease, but differences in frequency of reported side effects from baseline to follow-up (6-month time) were not significant, and the order of the frequency of the reported side effects remained similar. Patients who reported significant medication-related adverse effects reported significantly greater activity interference, negative affect, and catastrophizing compared with those with fewer side effects (<0.01). In addition, those patients with pain who reported more side effects showed significantly higher scores on opioid misuse risk (<0.001)."

According to the news reporters, the research concluded: "This study demonstrates the important role of monitoring medication-related side effects among patients with chronic pain who are prescribed opioid medication for pain within primary care."

For more information on this research see: Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care. Pain Reports, 2017;2(2):e589 (see also Opioids).

Our news journalists report that additional information may be obtained by contacting R.N. Jamison, Pain Management Center, Dept. of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. Additional authors for this research include K. Dorado, A. Mei, R.R. Edwards and M.O Martel.

The direct object identifier (DOI) for that additional information is: This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Keywords for this news article include: Boston, Opioids, Chronic Pain, Massachusetts, United States, North and Central America, Musculoskeletal Diseases and Conditions.

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